Scientific research on Unimate

Unimate is a highly purified yerba mate extract that’s been studied for its effects on satiety, mood, metabolic health, and cognitive function. The following pre-clinical and clinical studies explore its unique benefits and formulation.

Featured studies:

Effect of Unimate on acute appetite suppression among adults

Acute appetite responses to Unimate, a yerba mate supplement, were measured and compared to a flavor-matched placebo drink among a group of participants following a 12-hour overnight fast. Participants rated feelings of hunger, fullness, desire to eat, and other appetite-related measures for 120 minutes following consumption of Unimate or Placebo on 2 separate occasions. The overall trend in results show a decrease in desire to eat, feeling of hunger, and how much people thought they could eat, while fullness increased. Desire to eat was significantly reduced at 15, 30, and 45 minutes following Unimate consumption compared to baseline (0 min). These preliminary results suggest that Unimate supports appetite control, likely due to key components of the yerba mate extract, including caffeine, chlorogenic acid, theobromine, and mate saponins.

Daily Unimate intake promotes GLP-1 activity in the body

A preclinical study was conducted to evaluate the chronic effects of drinking Unimate on two key incretin hormones, glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP), which play important roles in regulating blood glucose, appetite, and metabolism. Further tests were performed to identify the active compounds in Unimate responsible for these effects. Experimental groups received either water (control) or Unimate daily for four weeks. Study results showed that Unimate significantly increased GLP-1 gene expression, which was accompanied by elevated GLP-1 levels in the body. This GLP-1 stimulating effect is likely driven by the gut microbiota, which converts a natural compound in Unimate into an active form that directly promotes GLP–1 production in the gut.